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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f82b55cc4c470a9ea168f1ba081436a17019a02e8542ebd498c20d4775e3e28' 
  AND token = '+UifMr/lEMCqyzH1tmUXZEVwMKqbPYlkVDDhqfeti5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}