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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a70a0c90f0afe734390bdc17edd1f8b3677ca826cf73589edc34092d46c92a' 
  AND token = 'ZC1ncef70CEzrIejVUdFxbupLsGJPINHt8VSWII3X8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}