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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678716176f2e0f46b71340e2fece7682cae8c874169b3d3dbe0361d1eb755e08' 
  AND token = 'mxAk/ICLPt+ziD038rR4THt1POypFxsiBRm41ZpR4/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}