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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557222cb5907244513d7f96cf58385c14622603170de863c7aeace38911725c7' 
  AND token = 'npWZ0D833mn8Setn9s4Mwc2af5EF9FF88LkBEfYKh9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}