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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b17109416162bb13b01168d9998950f8de0c5727f7e54e7b44124191871bf79' 
  AND token = 'l4zC7veyElQ/Hh0u0WsHtFw9ZhTeWZA3EkV8z7fC5mI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}