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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf256479b7ccff37ca4c6a73c30c8668ec51cad6f3af04af545c2b7643ac2a2' 
  AND token = 'kn9OvysA5tsGvekzDpY3kzVuvRH+FJTH4f3Qsri4dOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}