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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8788c29324d14f7aecc8a38e83ee5e41f754a991c5503c06ff04b9d1184b8c' 
  AND token = '9p37X4qSF88msla1ChwQX7k4QJFlUy8PUnZ1g3b1Uwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}