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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2494aa05a7ff90586574fbb09572b304e0e8070e10363b00761bec71f2b96965' 
  AND token = 'QyMrkENUd8dIA30YyG4ADbiyCKT0hxMs79tFmlTDKZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}