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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0b435ed2b6c7805b4a42cde5dbd49570ad2eabbb1a54a571a80d12c894d947b' 
  AND token = 'ZSO1mzLPdXLpHzevl6H2RtUsALmxuMpP3xoyx8tU6gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}