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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543237b14b2c2c9c0616b59e82ce5cf5c5c84daf7092f54709466e17294bb88c' 
  AND token = 'lzF71kD4EpWk9KFuLz5TF5IgwZoiWrNg2w5Cs9RKu90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}