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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07166c7fe8a3e343539698097625f41a01e462739078f18ae157193617995710' 
  AND token = 'mYp2DFUaQr7Yh7+M9a+lh9Dpv7t247ooVp6Rp37aDrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}