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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a2e337df31cf2934fd46f015f9074a065e55fad61967e4489fa18905e220a93' 
  AND token = '1CvUtYWMSr8aWHEejYR538OHyLcy0qzEguotTjXsxlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00079

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}