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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f643deb01e0c4716076c2609aad3fec7330fc8a3b866dc40f0e71e5d991d5f' 
  AND token = 'e/SX8mB7LsMgyPLsj5+pM78TXpK1cZNgF/dvNJjKV5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}