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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12368c45dc2cc07fde2d4e689cae21b517dce31174d2eeba141eadcd3e2c131' 
  AND token = 'ZxJa+qwU4zdbrLywpE0NWnvXEyEVTL5dHUrUqpf7Xag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}