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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8632eb0582155b7b5e5d482b7fc39501a36f24d745639668209ddd3528fc433' 
  AND token = 'Pir+VMASx4zN4nmjTchOFHD11WvPwnaWK9RVm3hc1tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}