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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd14ec045961423d0e2cb9a8db9264b7905afb7f99ceb750aca73b27f76ce03' 
  AND token = 'HZbDQ3HYVjHLsv7oV2VXXHdumrwWfZ6aiY4/heQSv0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}