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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe0f27ff1d99bd5c61f9a9018481a4c55d37b1198a6319bcd8f2dce5c04b15a' 
  AND token = 'dWz2vQGi4QSmlFCvDeq4kZ4UtGS/PTQ8nBywpSDxfe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}