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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed710c61045f6f89f0484f9aade633afca2931e91954f6df8b44b2766ce67e49' 
  AND token = 'nu6aVfT30FQgZ6+j1PQH1XMWZTebXOHBr/xXd9c6zjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}