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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5ca613b0eb5536efd050d0ee164dcdeb96d1720df04830aba4595059114dd3' 
  AND token = '8PvBnIqXHFQ4WG8vPD0eGh80QRoSuxWeCri5UUxZaNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}