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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b7eaf3ad4fa2ed77c1e91f785246e63f85831e7cbb408bf76cd836ea348607c' 
  AND token = '45A+DvDJuW/xUW0B7N1bjcJtYl47rHQPABwFaopbASk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}