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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5080b1bee016e500c0fa007532046101bcd9e6823cdae34f88a617a45de9676e' 
  AND token = 'VbmAdT/iujR/UrPjUu/niO3ec+SQ27+sPfy/ZY7Hd0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}