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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c10cc9433f0f20bae372034937bdc43c31d98d47e2663493bc863a33f854b3' 
  AND token = 'shzkc56qex8k3OePrRPHfyUNfsth/EbT7DuWIT8GAm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}