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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0de5c1e49b55f34136acc5c034c72cced68ddc37f0f56803b1d6285598ff2a4' 
  AND token = 'Vz9S4D95Nb/vy8wqSMEOfmzbfOcGRFEsxwvFpQTk6/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}