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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d3318d4c016d3768939c4130c430af1a5e93ab27a36795c07d49e6d9f94c029' 
  AND token = '7wHN7BFxvOZ9xqM5FyyF9nIz6Xx0pX6LYxFmc/56cRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}