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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e1a12bebc6de00747eaf509c19d7a8622a1e0ac9980bb8c736b3776305d07c' 
  AND token = 'P5WDS7VSMtIRifrn5SFKca+PvA/MBEIf6Lmh7Qp1m1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}