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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb1f51e856e6f20e2770220a6a515a9da704de1e43b76c70b7f385c38c309515' 
  AND token = 'VtYcz7+q4dBP0V9YDejUf7GdgqCmr1e10YSOKIzQVps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}