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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca21a20e190d002cb6eb5147d881e8995daadc73373a5732674981c2053051c' 
  AND token = 'tz6v5Rhf36AhVrolIflq/CGLsDkWV4+FrmAMeHXcS6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}