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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f591941108e8ac5c92dc6c471798a526b44303153ecbb3d36b563b3b3edb1b' 
  AND token = 'TvuUd4IoD4O/pPrmma2GFWlOSi3PPT/Lu3spFlamz9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}