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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeb06d9ed23785d1156f159864e80985256f9d569d75f8887ed081c4e9127d88' 
  AND token = 'oE8HDb/3JiEcwFQtQn20zKd2746+GwA18ypnla8seuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}