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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed647939849f4c75b09f2421ee77592053feb9affc8222b2ecc0e5342ae730b' 
  AND token = 'vt/A2T5cio4b0ZCRPl6qDHvB5/7IsFYaRtwlX0FGzbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}