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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c43cf75fe11247de942fb65e4e1f6aec70c58d49ec9a9b89c7217064281e90f' 
  AND token = 'LG/E6Sci9e+dlYwCP0htGhGCacGVPlO/DPdgv24gsuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}