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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9baa434e00289876bba5e94057b73b1c978e90621cda655ff5c6350c80da4705' 
  AND token = 'qOrh1Elljqta2+G2VqqgjBiH9mSzPtBG6APHkAPb4lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}