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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a1ea13834b1d9548e91a196a1987f68090e69755e67c64cc2c3f9966b5bbe8' 
  AND token = 'WU3viIwaCif+hmWSAMraTbjlFXWo4Mtv1To+GuDvzDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}