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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c659a387f29435708f10be5392f3f587815c3e2fc1a4e296ca32f4f3b3da5e5a' 
  AND token = 'yVMmLu76ONb55I+olTEmZwlpxnBBlYxoyWGnTSF6yPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}