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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '874ece5d20d44c060e2cb9b1fa18290c0a3bde6100a175f24bd4d288a0ed0d41' 
  AND token = 'te+TLSOqMwkK8XR0tqkUPIva+1pK0/ibAKiJe2tMxdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}