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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3cc7182f9aad018cc8db679b8a780f11bdcaf6bdcc2f1ea059b0fe42bf3bdba' 
  AND token = '2IcR2eHBZkM4pGxKN0nW/4cc58w0x/Vpb7C8tu1p/+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}