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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2be50512aa30b3cda00c181f12d383da167b417a5ca26065888e26fe8f0d128' 
  AND token = 'ecRfBvRFh5ncnsB4099LBR62detg5/b248UUFNeSf8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}