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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7876a21c20782e4c7b5f8f5dd151d54e8505b76c221d112680723dd1313b786' 
  AND token = 'veKXvOoQzDoL+hkHwOnt5/cC2oADKFgdIQ5Mj1VMd0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}