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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be3521bf294c39669432e748519006b942c67faf569da1e49a1e6be472af4b6' 
  AND token = 'JBE2RjiCtNPxlSMd854NaJF02qFVNjSX1HG9VrDfVj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}