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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c327b649797da1282f56d8436151dd9e3277a4799bd7d026feb63a1c30d9eb' 
  AND token = 'liEuTBt8CQTGVy4EThCO5V8s+F+bzx800IDB1m/It4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}