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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b03f50f7f3d6bd5e3e89b035860db892e41ad0829fbfa825ceb90391553dd652' 
  AND token = 'hjxzYkxZA3HxixBzgl9mzDvSTP8j3OTw4oFCQ9r6rJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}