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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8f142c4e462a16b539dfeb273745526d3dfda35e36c3d6ec4e7ff14ee008de4' 
  AND token = 'x+fjBMexc6v9H+S3LF60eYDF3H1I6TOmTgeSEyBRk2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}