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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae65e16ce4328b9af8ea38b1b499153a25747c62efef8047b18da8159c6a0785' 
  AND token = '5Kn7Wpr5LJBlejvdofKvOm1dZyGfwuy3jwCsfHU3Ito=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}