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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5ccaf13cb25c0d975fc9126a93acaab82b04482cabf8a1a28f302cc1d75194' 
  AND token = '3VByRizt6SsV9pVF9rY+csK7CE2C1QzxPjBVWbvWg/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}