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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49180576d592d50f9fc4343346ebb979c79edf888933f8b5bc25587ecb7f7c2c' 
  AND token = 'qkZXsL/ZEoTfV8r/mp3Jb6EY3tT3E+J4HaHtYgDTokI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}