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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a8e1bb4846144e0f8285c2dce1cfc3dc72831fd1f9caac1d933bf73d4c2d780' 
  AND token = 'FYYd3ZMSNh4FH8IrZFOJnk6+msGuTds2Vx6eJG96Fnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}