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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '528c7c20827eb852eda714c5329c1f92e7e40261e4092119be02ed92fbb02a34' 
  AND token = 'mcnPy3G0cgbmKqUEI6FJnU+F/QNlQLfZ3AFZfIOEwfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}