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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2efad50a1e35243a5d32c920eebb1ce23eb3d92ee5b1e1b6463b290ce37fed51' 
  AND token = '1rcDZagOpg8bgAvfmTUpRetNFIOgk792Ns94pfiLIJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}