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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e94b61078f47f88784ffc8221c31e00decd0787de8d4dac23c8583b4057625' 
  AND token = 'EcmIjK55ZIUsRZLY4ZBU6RAHKJ+5K2dIjQ1QsoYBRL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}