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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b61b80b1e6cb902e9f4ec4a4b0ac244c194fd86dee99f995da3a178fc728dc6' 
  AND token = 'Jimjse7XJ2wopzbgERKPUxxbpYukniCwKQUX//CqOf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}